Central States Pain Clinic

Ketamine Infusions

IV Ketamine infusions are used to treat various chronic pain syndromes that have a neuropathic component. Ketamine produces strong analgesia or numbing in neuropathic pain conditions by inhibition (blocking) of the N-methyl-D-aspartate (NMDA) receptor and by enhancement of descending inhibition and anti-inflammatory effects at central sites.

In clinical settings, ketamine is well tolerated, especially when benzodiazepines are used to modulate the psychotropic side effects. Close monitoring of patients receiving ketamine is necessary and the proposed treatment includes a safe environment with an anesthesia provider monitoring the patient during the infusion. 

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